Journal of Global Infectious DiseasesOfficial Publishing of INDUSEM and OPUS 12 Foundation, Inc. Users online:475  
Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size     
Home About us Editors Ahead of Print Current Issue Archives Search Instructions Subscribe Advertise Login 
Year : 2010  |  Volume : 2  |  Issue : 2  |  Page : 101-104

Synergistic properties of methylxanthine with cadmium and mercury on dermatophytes

Department of Clinical Laboratory, College of Pharmacy, University of Kerbala, Iraq

Correspondence Address:
Ali Abdul Hussein S AL-Janabi
Department of Clinical Laboratory, College of Pharmacy, University of Kerbala
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-777X.62878

Rights and Permissions

Background: Methylxanthine has many antimicrobial effects on different types of organisms. Synergism actions between methylxanthine and cadmium or mercury on dermatophytes were tested. Aims: To determine the synergistic property between methylxanthine and cadmium or mercury on the growth of dermatophytes. Materials and Methods: Two isolated strains of dermatophytes (Trichophyton mentagrophytes and Epidermophyton floccosum) that clinical isolated were treated with the mixtures of methylxanthine either with cadmium or with mercury by using colony diameter method. Percentage inhibition was also calculated based on perpendicular colony diameters of grown fungi. Results: Cadmium had high ability to increase inhibitory action of methylxanthine agents on dermatophytes. Epidermophyton floccosum revealed more susceptibility to tested mixture than those of Trichophyton mentagrophytes. Mercury exhibited variable effects on dermatophytes after mixing with methylxanthine. Conclusions : Effective concentrations of methylxanthine on dermatophytes decreased in the presence of cadmium and mercury. Variable susceptibility of two species of dermatophytes to prepared mixture was noted.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded52    
    Comments [Add]    

Recommend this journal


Sitemap | What's New | Feedback | Copyright and Disclaimer | Contact Us
2008 Journal of Global Infectious Diseases | Published by Wolters Kluwer - Medknow
Online since 10th December, 2008