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Year : 2017  |  Volume : 9  |  Issue : 2  |  Page : 66-72

Epidemiology of rotavirus in the Iranian children: A systematic review and meta-analysis

1 Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
2 Department of Mycobacteriology and Pulmonary Research, Pasteur Institute, Tehran, Iran
3 Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
4 Department of Nutrition, School of Health, Zabol University of Medical Sciences, Zabol, Iran
5 Department of Microbiology, School of Medicine, Kermanshah University of Medical Science, Kermanshah, Iran

Correspondence Address:
Mohsen Moghoofei
Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-777X.205173

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Rotavirus is associated with increased risk for severe diarrhea in infants and young children worldwide. This systematic review and meta-analysis was performed to determine the prevalence rate of rotavirus from different parts of Iran and provide an overall relative frequency (RF) for Iran. We performed a systematic literature review from several databases including PubMed, ISI Web of Science, Scopus, OVID, MAG IRAN, IranMedex, and Iranian Scientific Information Database. We searched the following keywords: “rotavirus,” “rotavirus infection,” “acute gastroenteritis,” “diarrhea,” “children,” “infant,” and “Iran.” The purpose of this study was to report the prevalence of rotavirus with the application of meta-analysis. We selected 43 researches out of 1147 for our study. From all the samples, the pooled estimate of prevalence (95% confidence interval) =39.9% (0.396%–0.409%) were rotavirus positive. It should be noted that rotavirus infection's RF varied from 6.4% to 79.3% in Birjand and Tehran Provinces, respectively. Thereupon, it is divergent in different studies. According to our study result, rotavirus RF has a wide range in Iran and is associated with diarrhea in children. Thus, further researches should be taken to minimize the emergence and transmission of rotavirus.

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2008 Journal of Global Infectious Diseases | Published by Wolters Kluwer - Medknow
Online since 10th December, 2008