| ORIGINAL ARTICLE |
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| Year : 2018 | Volume
: 10
| Issue : 4 | Page : 222-225 |
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Extended-spectrum beta-lactamase-producing community-acquired urinary tract infections in children: Chart review of risk factors
Sundaram Balasubramanian, Dhanalakshmi Kuppuswamy, Swathi Padmanabhan, Vaishnavi Chandramohan, Sumanth Amperayani
Department of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital and CHILDS Trust Medical Research Foundation, Chennai, Tamil Nadu, India
Correspondence Address:
Dr. Sundaram Balasubramanian
Kanchi Kamakoti Childs Trust Hospital and The Childs Trust, Medical Research Foundation, 12-A, Nageswara Road, Nungambakkam, Chennai - 600 034, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-777X.246391
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Background: Community acquired urinary tract infections (CA-UTI) caused by extended spectrum beta lactamase (ESBL) producing organisms is on the rise throughout the world. There are known risk factors such as age <1 year, children on uroprophylaxis, recurrent UTI, recent antibiotic usage etc which can predict the occurrence of these ESBL producers. Objectives: To correlate known risk factors with occurrence of ESBL UTI and antibiotic susceptibility of uropathogens isolated. Materials and Methods: Clinical and microbiological data were collected from 100 children 1month to 12 years with CA-UTI. The risk factors were compared in the ESBL and non-ESBL group and analysed. Results and Conclusion: The antimicrobial sensitivity pattern in our study showed increased resistance to cephalosporins, cotrimoxazole, fluoroquinolones and amoxicillin-clavulanic acid which are frequently used in the treatment of UTI, with most isolates being sensitive to aminoglycosides, piperacillin-tazobactam and carbapenems. Statistical analysis did not identify any significant risk factor that predisposes to ESBL UTI.
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